Thermo Fisher Scientific SPACA3 Polyclonal Antibody
SPACA3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 액상 형태로 -20°C 보관. 면역치료 연구용으로 활용 가능.
- 카탈로그번호
- SPACA3-331AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides within amino acid regions 50–100 and 80–130 of human SPACA3 isoform 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPACA3 (Sperm Acrosome Associated 3), also known as sperm lysozyme-like protein 1 (LYC3), SPRASA, or LYZL3, is a 215 amino acid protein involved in sperm-egg plasma membrane adhesion and fusion during fertilization.
It is expressed in testis, placenta, and epididymis, and exists as two isoforms:
- Isoform 1: Single-pass type II membrane protein of the sperm acrosome
- Isoform 2: Secreted protein
SPACA3 is identified as a novel cancer/testis antigen capable of eliciting B-cell immune responses in cancer patients, making it a potential immunotherapy target.
The processed form has no detectable bacteriolytic activity in vitro.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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