Thermo Fisher Scientific SPACA3 Polyclonal Antibody
SPACA3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot, ELISA, IP에 적합하며, 인간, 생쥐, 랫드 반응성. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides within amino acid region 20–70 of human sperm acrosome membrane-associated protein 3 isoform 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA, or LYZL3, is a 215 amino acid protein involved in sperm–egg plasma membrane fusion and adhesion during fertilization.
It is a member of the glycosyl hydrolase 22 family, expressed in testis, placenta, and epididymis.
SPACA3 exists as two alternatively spliced isoforms:
- Isoform 1: single-pass type II membrane protein in the sperm acrosome
- Isoform 2: secreted protein
SPACA3 may act as a receptor for egg oligosaccharide residues (N-acetylglucosamine) and is considered a potential immunotherapy target due to its role as a cancer/testis antigen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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