Thermo Fisher Scientific CD157 Monoclonal Antibody (eBioSY11B5 (SY11B5)), APC, eBioscience
인간 CD157를 인식하는 마우스 단클론 항체로, APC 형광 표지되어 유세포 분석(Flow Cytometry)에 최적화됨. BST-1 단백질 연구에 적합하며, 633–647 nm 레이저에서 660 nm 방출. 4°C 암조건 보관, 동결 금지.
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Thermo Fisher Scientific CD157 Monoclonal Antibody (eBioSY11B5 (SY11B5)), APC, eBioscience™
Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.125 µg)/test
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | eBioSY11B5 (SY11B5) |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573166 |
Available Conjugate Formats
- Unconjugated
- Alexa Fluor 488
- NovaFluor Blue 660-120S
- NovaFluor Red 710
- NovaFluor Yellow 590
- NovaFluor Yellow 610
- PE
- PE-Cyanine7
- Super Bright 436
- Super Bright 600
- Request custom conjugation
Product Specific Information
The eBioSY11B5 monoclonal antibody recognizes human CD157 (Mo5, BST-1).
CD157 is a 42–45 kDa GPI-anchored protein structurally and functionally related to CD38. It was initially identified for its expression on monocytes and macrophages and later found to be identical to BST-1, expressed on bone marrow stromal cells. CD157 acts as both an enzyme and receptor, involved in NAD⁺ metabolism and intracellular Ca²⁺ regulation. Upon ligand binding, CD157 can initiate a signal transduction cascade leading to phosphorylation of cytoplasmic proteins such as focal adhesion kinase (FAK).
- Applications Reported: Flow cytometric analysis
- Applications Tested: Pre-titrated for use at 5 µL (0.125 µg)/test
- Defined as the amount of antibody required to stain a cell sample in 100 µL final volume
- Recommended cell number: 10⁵–10⁸ cells/test
- Excitation: 633–647 nm
- Emission: 660 nm
- Laser: Red Laser
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
Bone marrow stromal cell antigen 1 (BST1) is a GPI-anchored molecule that promotes pre-B cell growth. Also known as ADP-ribosyl cyclase 2 and DAMP-1, BST1 expression is enhanced in bone marrow stromal cell lines from rheumatoid arthritis patients. Overexpression of BST1 may contribute to B cell abnormalities in rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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