Thermo Fisher Scientific Phospho-CD79a (Tyr199) Polyclonal Antibody
CD79a 단백질의 Tyr199 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot과 IHC(P)에서 사용 가능. 사람, 생쥐, 랫트 반응성. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CD79A (Accession P11912), corresponding to amino acid residues around phosphorylated Tyr199. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816915 |
Product Specific Information
This antibody detects endogenous levels of CD79A only when phosphorylated at Tyr199.
Target Information
CD79a is a disulphide-linked heterodimer that includes the B29 (CD79b) polypeptide. It functions as part of the B lymphocyte antigen receptor complex, associating with Ig-alpha and Ig-beta, which are essential for the expression and function of the B-cell antigen receptor.
CD79a first appears at the pre-B cell stage and persists until the plasma cell stage, where it is found intracellularly. It is expressed in most acute leukemias of precursor B-cell type, B cell lines, B cell lymphomas, and some myelomas, but not in myeloid or T cell lines.
Diseases associated with CD79a include Agammaglobulinemia 3 and Agammaglobulinemia, Non-Bruton type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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