Thermo Fisher Scientific DEFA4 Polyclonal Antibody
Thermo Fisher Scientific의 DEFA4 폴리클로날 항체는 인간, 마우스, 랫트 반응성을 가지며 Western blot 및 IHC(P) 분석에 적합합니다. 합성 펩타이드로부터 유래한 면역원으로 제작되었으며, 액상 형태로 1 mg/mL 농도입니다. 연구용으로 사용되며 높은 특이성과 재현성을 제공합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DEFA4 (Accession P12838), corresponding to amino acid residues I3–A53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852494 |
Product Specific Information
Antibody detects endogenous levels of total Defensin alpha 4.
Target Information
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in neutrophils; it exhibits corticostatic activity and inhibits corticotropin-stimulated corticosterone production.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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