Thermo Fisher Scientific Phospho-ATF4 (Ser219) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000
• View 1 publication

Product Specifications

Product Specific Information

Antibody detects endogenous levels of ATF4 only when phosphorylated at Ser219.

Target Information

This gene encodes a transcription factor originally identified as a widely expressed mammalian DNA-binding protein that binds a tax-responsive enhancer element in the LTR of HTLV-1. It is also known as cAMP-response element binding protein 2 (CREB-2). The encoded protein belongs to a family of DNA-binding proteins, including the AP-1 family, CREBs, and CREB-like proteins. These transcription factors share a leucine zipper region involved in protein-protein interactions, located C-terminal to a basic DNA-binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 within a large inverted duplication region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.