Thermo Fisher Scientific Growth Hormone Recombinant Mouse Monoclonal Antibody (rGH, 4887)
Recombinant mouse monoclonal antibody specific for human growth hormone (GH1). Validated for IHC-P with high specificity and reproducibility. Produced in HEK293 cells and purified by Protein A/G. Supplied as liquid form, 1 mg/mL, for research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC-P)
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rGH, 4887 |
| Immunogen | Recombinant full-length human GH1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C (preferred) |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For IHC of PFA-fixed tissues: incubate antibody for 30 min at room temperature.
- For formalin-fixed tissues: heat sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, then cool at room temperature for 20 min.
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family involved in growth regulation.
The GH1 gene, located on chromosome 17, is part of a locus containing five highly similar genes.
Alternative splicing produces isoforms of 19–24 kDa.
hGH is secreted by pituitary somatotroph cells and acts via cytokine receptor family members.
It promotes growth by stimulating IGF-1 secretion, myoblast differentiation and proliferation, and protein synthesis.
Mutations or deletions in GH1 cause growth hormone deficiency and short stature.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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