Thermo Fisher Scientific Thrombomodulin/CD141 Recombinant Mouse Monoclonal Antibody (rTHBD, 1591)
인간 Thrombomodulin/CD141 단백질을 인식하는 마우스 유래 재조합 단클론 항체입니다. IHC(P) 및 Peptide Array에 사용 가능하며, HEK293 세포에서 발현되었습니다. Protein A/G로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 7056-MSM3-P1
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rTHBD, 1591 |
| Immunogen | Recombinant fragment (around aa 69–194) of human Thrombomodulin (CD141) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
Thrombomodulin (TM), also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112, contains six repeated domains homologous with epidermal growth factor (EGF) and an amino-terminal domain homologous to lectin-like protein.
Through its accelerated activation of protein C, TM synthesis plays a key role in maintaining thrombo-resistance, reducing clot formation on the endothelial cell surface.
Immunohistochemical staining of formalin-fixed tissues for TM has been used in studies of vascular tumors, meningiomas, and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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