Thermo Fisher Scientific Thrombomodulin/CD141 Monoclonal Antibody (THBD, 1782)
인간 Thrombomodulin/CD141 단백질을 인식하는 단클론 항체로, IHC(P) 및 Peptide Array에 적합합니다. Protein A/G로 정제된 액상 형태이며, 보존제가 포함되지 않습니다. 혈관성 종양 및 내피세포 연구에 유용합니다.
- 카탈로그번호
- 7056-MSM2-P1ABX
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | THBD, 1782 |
| Immunogen | Recombinant fragment (around aa 69–194) of human Thrombomodulin (CD141) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | –20°C or –80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Antibody is tested in direct ELISA (use 2–4 µg/mL for coating).
- For immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
Thrombomodulin (TM), also known as Fetomodulin (FM), endothelial anticoagulant protein, or glycoprotein P112, is a glycoprotein expressed on endothelial cells. It contains six EGF-like domains and a lectin-like amino terminal domain. TM accelerates activation of protein C, playing a crucial role in maintaining thrombo-resistance and preventing clot formation on endothelial surfaces. Immunohistochemical staining for TM is useful in studying vascular tumors, meningiomas, and choriocarcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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