Thermo Fisher Scientific CD44v4 Monoclonal Antibody (VFF-11)

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Heat-mediated antigen retrieval using a sodium citrate buffer (pH 6.0) is recommended for staining of paraffin sections.
• For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.

Target Information

CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and by some epithelial cells of the intestine and breast.
Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 acts as a receptor for hyaluronic acid (HA) and plays roles in cell-cell interactions, adhesion, and migration.
It is also involved in lymphocyte activation, recirculation, and homing.
CD44 expression may be upregulated in some carcinomas and may be associated with metastatic potential.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.