Thermo Fisher Scientific DDX56 Monoclonal Antibody (UMAB152), UltraMAB
DDX56 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot, IHC, ICC/IF, ChIP 등 다양한 응용에 적합합니다. Human 시료에 반응하며, PBS 기반 완충액에 동결건조 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:200 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB152 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 323–547 of human DDX56 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The DDX56 gene encodes a member of the DEAD box protein family, characterized by the conserved Asp-Glu-Ala-Asp (DEAD) motif. These proteins are putative RNA helicases involved in various cellular processes requiring RNA secondary structure modification, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.
Some family members are implicated in embryogenesis, spermatogenesis, and cellular growth and division. The DDX56 protein exhibits ATPase activity in the presence of polynucleotides and associates with nucleoplasmic 65S preribosomal particles, suggesting a role in ribosome synthesis, particularly during assembly of the large 60S ribosomal subunit.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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