Thermo Fisher Scientific PLAC1 Polyclonal Antibody
인체 PLAC1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 분석에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 단기 4°C, 장기 -20°C 보관. 암 연구 및 면역치료 타깃 연구에 활용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the non-phosphorylation site at Serine 156 surrounding the epitope -LSQSSQRP- of human Placenta-specific 1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with proprietary stabilizer |
| Contains | 0.01% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive control: MCF-7
- Cellular location: Membrane
Target Information
PLAC1 was initially identified as a protein expressed specifically in the placenta and trophoblast-derived cells during embryonic development. It is also ectopically expressed in various human malignancies, particularly breast cancers.
PLAC1 is a membrane-associated protein with receptor-like functions modulating cell-cell or ligand-receptor interactions at the maternal-placental interface.
Reduced PLAC1 expression correlates with decreased cyclin D1 and AKT kinase levels. Because PLAC1 is expressed on cancer cell surfaces, it may serve as a promising immunotherapeutic target.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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