Protein Characterization

To help clients generate the data needed to gain the level of product characterization required for regulatory submission, Charles River offers protein analysis as part of an integrated package of expert analytical services. We have extensive experience in developing and establishing protein characterization methods, including product-specific in vitro potency assays. These characterization services are also a part of our stability and product release support services, where we offer key identity, purity and potency assays.

Protein Analysis

Charles River has the technologies and instrumentation to support your research through all phases of development, from Pre-IND to BLA. As an advanced analytical laboratory, we serve clients who require expertise in recombinant glycoprotein and complex biologics characterization services. We specialize in a broad range of analytical testing techniques to support characterization and development of both recombinant protein and peptide therapeutics. Our team of experts, complemented by our cutting-edge technology, supports our clients while upholding the highest standards of quality, technical analysis, and reporting.

• Mass Spectrometry
• Biophysical Characterization
• Glycosylation / Glycan Characterization
• Chromatography & Electrophoretic Methods
• N-terminal Sequencing & Amino Acid Analysis
• ELISA & Immunoassay Development
• Protein Formulation Development
• Glycoprotein Characterization
• Antibody-Drug & Other Conjugates
• Liposomal Product Characterization
• Recombinant Adeno-Associated Virus Products
• Reference Standard Characterization & Support
• Product Experience