Thermo Fisher Scientific WIBG Monoclonal Antibody (UMAB209), UltraMAB
인간 WIBG 단백질을 인식하는 UMAB209 클론의 마우스 단일클론 항체로, Western blot, IHC, ICC, ChIP, Peptide Array 등에 사용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며 연구용으로 적합.
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Thermo Fisher Scientific WIBG Monoclonal Antibody (UMAB209), UltraMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:400 |
| Immunocytochemistry (ICC/IF) | 1:100–1:400 |
| ChIP assay (ChIP) | Assay-dependent |
| Peptide Array (Array) | 1:100 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | UMAB209 |
| Immunogen | Full-length human recombinant WIBG protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
WIBG is a key regulator of the exon junction complex (EJC), a multiprotein complex that associates upstream of exon-exon junctions on mRNAs. It serves as a positional landmark for post-transcriptional processes such as mRNA export, nonsense-mediated mRNA decay (NMD), and translation. WIBG acts as an EJC disassembly factor, facilitating translation-dependent EJC removal and recycling. It may bind RNA; however, the biological relevance remains unclear. [UniProt]
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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