Thermo Fisher Scientific MCM7 Polyclonal Antibody
Rabbit polyclonal antibody against MCM7 protein. Suitable for Western blot and immunoprecipitation. Supplied as liquid, 1 mg/mL concentration. Recommended storage at 4°C. For research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 669 and 719 of human MCM7 (UniProt ID: P33993-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and recruitment of other DNA replication-related proteins.
The MCM complex consisting of MCM2, 4, 6, and 7 proteins possesses DNA helicase activity and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase CDK4 associates with this protein and may regulate its interaction with the tumor suppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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