Thermo Fisher Scientific MCM7 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MCM7 protein. Validated for WB and IP applications. High specificity and affinity-purified. Supplied as liquid at 1 mg/mL in tris citrate/phosphate buffer with sodium azide. Recommended storage at 4°C, shipped...
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 500 and 550 of human minichromosome maintenance deficient 7 (MCM7) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse and Bovine
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance (MCM) proteins essential for the initiation of eukaryotic genome replication. The hexameric complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in replication fork formation and recruitment of other DNA replication-related proteins. The MCM complex, including MCM2, 4, 6, and 7, possesses DNA helicase activity and may function as a DNA unwinding enzyme. Cyclin D1-dependent kinase CDK4 is known to associate with this protein and may regulate its interaction with the tumor suppressor RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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