Thermo Fisher Scientific MCM7 Polyclonal Antibody
Rabbit polyclonal antibody against human MCM7 protein for WB and IP applications. Recognizes residues 300–350 of MCM7. Supplied as liquid, unconjugated form at 0.2 mg/mL. Stored at 4°C, shipped on wet ice. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and 350 of human minichromosome maintenance deficient 7 (MCM7) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication.
The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and recruitment of other DNA replication-related proteins.
The MCM complex consisting of MCM2, 4, 6, and 7 possesses DNA helicase activity and may act as a DNA unwinding enzyme.
Cyclin D1-dependent kinase CDK4 associates with MCM7 and may regulate its binding with the tumor suppressor protein RB1/RB.
Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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