Thermo Fisher Scientific MCM7 Polyclonal Antibody
Rabbit polyclonal antibody targeting MCM7 protein for research use. Unconjugated liquid form with 1 mg/mL concentration. Essential for studying eukaryotic DNA replication mechanisms. Stored at 4°C and shipped on wet ice.
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Thermo Fisher Scientific MCM7 Polyclonal Antibody
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Between amino acids 669 and 719 of MCM7 (UniProt ID: P33993-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may participate in replication fork formation and recruitment of other DNA replication-related proteins.
The MCM complex (MCM2, 4, 6, and 7) possesses DNA helicase activity and may function as a DNA unwinding enzyme. Cyclin D1-dependent kinase CDK4 associates with MCM7 and may regulate its binding with tumor suppressor protein RB1/RB.
Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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