Thermo Fisher Scientific KCNJ10 Polyclonal Antibody
KCNJ10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 검증됨. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:3,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from amino acid region 330–379 of human KCNJ10 conjugated to a blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in rat and mouse.
- Specificity: KCNJ10.
Target Information
The KIR (inwardly rectifying potassium channel) family of potassium channels allows potassium ions to flow more readily into the cell than out.
KIR4.1 (KCNJ10) is highly expressed in the brain, including glial cells, astrocytes, and cortical neurons. It is also found in myelin-synthesizing oligodendrocytes and plays a crucial role in myelination during nervous system development.
The human KIR4.1 gene maps to chromosome 1.
KIR4.2, expressed in kidney, lung, heart, thymus, and thyroid, maps to chromosome 21 and may be associated with Down syndrome pathogenesis.
KIR5.1 forms functional channels only when coexpressed with KIR4.1 or KIR4.2 in the kidney and pancreas.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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