Thermo Fisher Scientific KCNJ10 Polyclonal Antibody
KCNJ10 단백질을 표적하는 Thermo Fisher Scientific의 폴리클로날 항체로, WB 및 IHC에 적합합니다. Rabbit IgG로 제작되었으며, 인간·마우스·랫트 반응성을 보입니다. 합성 펩타이드(aa 330–379)를 면역원으로 사용하며, 연구용으로만 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10–50 µg/mL |
| Immunohistochemistry (IHC) | 10–50 µg/mL |
| Miscellaneous (PubMed) | – |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 330–379 of human KCNJ10 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: KCNJ10.
Target Information
The KIR (inwardly rectifying potassium channel) family allows potassium to flow preferentially into the cell.
KIR4.1 (Kir1.2) is highly expressed in brain tissue, including glial cells, astrocytes, and cortical neurons.
It is also found in myelin-synthesizing oligodendrocytes and is essential for myelination during nervous system development.
The human KIR4.1 gene is located on chromosome 1.
KIR4.2 (Kir1.3) is expressed in kidney, lung, heart, thymus, and thyroid during development and maps to chromosome 21, possibly linked to Down syndrome pathogenesis.
KIR5.1 forms functional channels only when coexpressed with KIR4.1 or KIR4.2 in kidney and pancreas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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