Thermo Fisher Scientific Cathepsin A Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Antibody로 Cathepsin A 단백질 검출에 사용. Western Blot에 적합하며 높은 순도(>95%) 확보. Antigen affinity chromatography로 정제된 액상형 제품. 연구용으로만 사용 가능.
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- PA586868
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- pk
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues in Human CTSA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2803627 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
The cathepsin family of proteolytic enzymes includes several diverse classes of proteases.
Cathepsins B, L, H, K, S, and O comprise the cysteine protease class.
Cathepsins D and E comprise the aspartyle protease class.
The serine protease class includes cathepsin G.
Cathepsins function in cellular metabolism and participate in peptide biosynthesis and protein degradation.
Cathepsin A, a serine carboxypeptidase, exists in a high molecular weight lysosomal complex with β-galactosidase (β-gal) and α-neuraminidase (Neu1).
Cathepsin A protects β-gal and Neu1 from intralysosomal proteolysis.
Deficiencies in cathepsin A lead to deficiencies in β-gal and Neu1.
The gene encoding human cathepsin A maps to chromosome 20q13.12.
Mutations in this gene cause galactosialidosis, a lysosomal storage disorder resulting from β-gal and Neu1 deficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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