Thermo Fisher Scientific FNTB Recombinant Rabbit Monoclonal Antibody (SC06-44)
FNTB 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 면역세포염색(ICC/IF)에 적합합니다. 높은 특이성과 재현성을 제공하며, 동물 유래 성분이 없는 포뮬레이션으로 제조되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SC06-44 |
| Immunogen | Recombinant protein within Human FNTB (aa 1–98) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809546 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to rabbit immune repertoire
Target Information
Eukaryotic cells contain three types of prenyltransferases that attach either a farnesyl group (15 carbons) or a geranylgeranyl group (20 carbons) via thioether linkage to C-terminal cysteine residues in various proteins. These posttranslational modifications enable membrane localization of proteins lacking transmembrane domains.
CAAX farnesyltransferase (FTase) transfers a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins ending in the CAAX box (C = cysteine, A = aliphatic amino acid, X = typically methionine or serine). The FNTB gene, encoding the beta subunit of FTase, is located at 14q23–q24 in humans.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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