Thermo Fisher Scientific BAD Monoclonal Antibody (E.564.7)
BAD 단백질을 인식하는 고특이성 Rabbit Monoclonal Antibody (Clone E.564.7). Western blot 및 Immunocytochemistry에 적합. 인간, 마우스, 원숭이, 랫트 반응성. 액상 형태로 제공되며 -20°C 보관. 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | E.564.7 |
| Immunogen | Synthetic peptide corresponding to residues surrounding Pro102 of human Bad |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 27.9 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | <0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_10986345 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- This antibody is not cross-reactive with related proteins.
Target Information
The protein encoded by BAD is a member of the BCL-2 family, which regulates programmed cell death. BAD promotes apoptosis by forming heterodimers with BCL-xL and BCL-2, reversing their death repressor activity. Its proapoptotic activity is regulated through phosphorylation by kinases such as AKT and MAP kinase, and by phosphatase calcineurin. Alternative splicing results in two transcript variants encoding the same isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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