Thermo Fisher Scientific LRFN1 Polyclonal Antibody
LRFN1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB와 IHC에 적합합니다. 인간, 마우스, 랫트 반응성을 가지며 항원 친화 크로마토그래피로 정제되었습니다. 신경조직 내 LRFN 단백질 연구에 유용합니다.
- 카탈로그번호
- PA520698
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (IHC) | 2.5 µg/mL | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | An 18 amino acid peptide near the carboxy terminus of human LRFN1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154355 |
Product Specific Information
- A suggested positive control is human brain tissue lysate.
- PA5-20698 can be used with blocking peptide PEP-0813.
Target Information
LRFN1 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues.
LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins.
Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells.
LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery.
It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.
At least two isoforms of LRFN1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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