Thermo Fisher Scientific GNPDA2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (IHC)

20 µg/mL

-

Immunocytochemistry (ICC/IF)

4 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

an 8 amino acid peptide near the carboxy terminus of human GNPDA2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GNPDA2,uniProtId:Q8TDQ7-1,ncbiNodeId:9606,antigenRange:276,antigenLength:276,antigenImageFileName:PA5-20694_GNPDA2_Q8TDQ7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-20694_GNPDA2_Q8TDQ7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_11152535

Product Specific Information

A suggested positive control is human kidney tissue lysate.

PA5-20694 can be used with blocking peptide PEP-0809.

Target Information

GNPDA2 (Glucosamine-6-phosphate deaminase) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.