Thermo Fisher Scientific IRF2 Recombinant Rabbit Monoclonal Antibody (8M2N4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

8M2N4

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 250-349 of human IRF2 (P14316). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IRF2,uniProtId:P14316-1,ncbiNodeId:9606,antigenRange:250-349,antigenLength:349,antigenImageFileName:MA5-42862_IRF2_P14316-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42862_IRF2_P14316-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.05 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912003

Product Specific Information

Positive test controls include: HeLa. The target is usually found in the following locations: Nucleus.

Immunogen sequence: PHWRKRNIEG KQYLSNMGTR GSYLLPGMAS FVTSNKPDLQ VTIKEESNPV PYNSSWPPFQ DLPLSSSMTP ASSSSRPDRE TRASVIKKTS DITQARVKSC

Target Information

IRF2 belongs to the interferon regulatory factor family. IRF2 regulates the transcription regulation important to cell proliferation as well as immune responses by binding to the upstream regulatory region of type I IFN and IFNinducible MHC class I genes (the interferon consensus sequence (ICS)) and repression of those genes. However, IRF2 also functions as a transcriptional activator of histone H4 by interactions with NF-kappa B.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.