Thermo Fisher Scientific SCARA5 Polyclonal Antibody
SCARA5 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunocytochemistry에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼와 0.02% sodium azide 포함. 인체 반응성 확인 및 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunocytochemistry (ICC/IF) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 17 amino acid peptide near the carboxy terminus of human SCARA5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11154677 |
Product Specific Information
- Suggested positive control: human spleen tissue lysate
- PA5-20766 can be used with blocking peptide PEP-0880.
Target Information
Scavenger receptor class A member 5 (SCARA5), also known as TESR, is part of the scavenger receptor superfamily, composed of members with diverse structures, expression patterns, and functions.
SCARA5 is a cell-surface receptor containing a collagen-like domain and N-terminal scavenger receptor cysteine-rich domain typical of class A scavenger receptors.
Unlike other class A receptors, SCARA5 does not endocytose acetylated or oxidized low-density lipoprotein. Instead, it binds serum ferritin and mediates its endocytosis from the cell surface, suggesting a role in non-transferrin iron delivery.
At least four isoforms of SCARB1 are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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