Thermo Fisher Scientific MMP12 Monoclonal Antibody (1A4)
MMP12 단백질을 인식하는 Rabbit IgG 단일클론 항체로, Western blot, IHC, Flow cytometry 등 다양한 응용에 적합합니다. 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A4 |
| Immunogen | Recombinant human MMP12 between 450 amino acids to C-terminus |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
Matrix metalloproteinase (MMP) family proteins are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes like arthritis and metastasis. Most MMPs are secreted as inactive proproteins that are activated when cleaved by extracellular proteinases. The MMP12 enzyme degrades soluble and insoluble elastin and may play a role in aneurysm formation and emphysema development. The gene is part of a cluster of MMP genes localized to chromosome 11q22.3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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