Thermo Fisher Scientific STAT6 Monoclonal Antibody (9A7)
STAT6 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체로, 다양한 면역실험(WB, IHC, ICC, Flow)에 적용 가능. IL-4 및 IL-13 관련 Th2 면역반응 연구에 적합. 고순도 액상 형태로 -20°C 보관. 연구용 전용 제품.
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Thermo Fisher Scientific STAT6 Monoclonal Antibody (9A7)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:400 |
| Immunocytochemistry (ICC/IF) | 1:200 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 9A7 |
| Immunogen | Recombinant human STAT6 protein, around residues 700–800 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Target Information
STAT6 protein is a transcription factor activated by cytokines, particularly interleukin-4 and IL-13. STAT6-deficient (Stat6-/-) models show loss of IL-4-mediated functions including Th2 helper T-cell differentiation, expression of surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and partial loss of IL-4-mediated proliferation.
STAT6 mRNA has been detected in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta.
STAT6 is critically involved in Th2 immune response and IL-4-mediated biological processes, existing naturally in two isoforms: STAT6a and STAT6c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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