Thermo Fisher Scientific GEMIN8 Monoclonal Antibody (OTI1A8), TrueMAB
GEMIN8 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 적합합니다. 인간 유래 단백질을 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 친화 크로마토그래피로 정제되었고, 안정적인 PBS/BSA/glycerol 완충액에 보관됩니다.
- 카탈로그번호
- TA805833
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:2,000 희석 배율로 테스트됨
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A8 |
| Immunogen | Full length human recombinant protein of human GEMIN8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The SMN complex plays a catalytic role in the assembly of small nuclear ribonucleoproteins (snRNPs), which are essential components of the spliceosome. It is crucial for the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins (SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, and SNRPG) that assemble into a heptameric ring on the Sm site of small nuclear RNA to form the core snRNP. In the cytosol, these Sm proteins are initially held in an inactive 6S pICln-Sm complex by the chaperone CLNS1A. The SMN complex mediates dissociation of CLNS1A and facilitates the formation and nuclear transport of core snRNPs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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