Thermo Fisher Scientific TIP47 Polyclonal Antibody
TIP47 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합하며, 인간과 마우스 시료 반응성 확인. 항원 친화 크로마토그래피로 정제된 액상 항체로, TBS buffer와 sodium azide 함유. 연구용 전용 제품.
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Thermo Fisher Scientific TIP47 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:500 | – |
Product Specifications
| Category | Details |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 1–100 of mouse TIP47 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2139115 |
Product Specific Information
In Western Blot analysis, a band is observed around 47 kDa (isoform B, containing the first 184 residues absent in isoform A).
Suggested positive controls: HeLa whole cell lysate and 3T3 L1 lysate.
Target Information
TIP47 is a cargo protein involved in trafficking of mannose-6-phosphate receptors (MPRs) between endosomes and the Golgi complex.
It interacts with cytoplasmic domains of both cation-independent and cation-dependent MPRs and is essential for endosome-to-Golgi transport.
TIP47 also binds directly to GTPase RAB9, increasing its affinity for cargo.
The protein has been localized in milk fat globule membranes of human and bovine origin and described as a placental protein.
Elevated TIP47 levels are found in circulation of cervix carcinoma patients, suggesting its role as a potential oncodevelopmental marker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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