Thermo Fisher Scientific Ksp-Cadherin (Kidney-Specific Cadherin)/CDH16 Monoclonal Antibody (CDH16/1071)
Kidney-specific cadherin(CDH16)을 인식하는 mouse monoclonal antibody로, WB, IHC, Flow, ELISA 등 다양한 응용 가능. Dog, Human, Mouse, Rabbit, Rat 반응성. Protein A/G 정제, PBS buffer, preservative 없음. 연구용 한정.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | 2–4 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rabbit, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CDH16/1071 |
| Immunogen | Recombinant full-length human CDH16 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cadherins are a family of Ca²⁺-dependent adhesion molecules that mediate cell-cell binding, essential for structural maintenance and morphogenesis. Each cadherin has a large extracellular domain with five homologous repeats, where the distal repeat determines binding specificity.
Cadherin-16 (Ksp-Cadherin) is a type I membrane protein expressed specifically in the kidney, localized to the basolateral membrane of renal tubular epithelial cells.
The human Cadherin-16 gene maps to chromosome 16q21–proximal 16q22, while the mouse gene is found in a syntenic region of distal chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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