Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI15E3), TrueMAB
Human NKX2-1 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot에 최적화됨. Lyophilized 형태이며 PBS buffer에 trehalose 포함. 연구용으로 사용되며 thyroid-specific transcription factor 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI15E3 |
| Immunogen | Full length human recombinant protein of human NKX2-1 (NP_003308) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a protein identified as a thyroid-specific transcription factor. It binds to the thyroglobulin promoter and regulates thyroid-specific gene expression, as well as genes involved in morphogenesis.
Mutations or deletions are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, neonatal respiratory distress, and potentially thyroid cancer.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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