Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI15A10), TrueMAB

Applications

• Western Blot (WB): 1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

The NKX2-1 gene encodes a thyroid-specific transcription factor that binds to the thyroglobulin promoter and regulates thyroid-specific gene expression. It also influences genes involved in morphogenesis.
Mutations or deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, neonatal respiratory distress, and potentially thyroid cancer.
Multiple transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.