Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI15A10), TrueMAB
Human NKX2-1 단백질을 인식하는 Mouse Monoclonal Antibody로 Western Blot에 적합. Lyophilized 형태로 제공되며, PBS buffer와 trehalose 포함. 연구용 전용 제품으로 안정적 보관 및 재구성이 용이.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI15A10 |
| Immunogen | Full length human recombinant protein of NKX2-1 (NP_003308) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NKX2-1 gene encodes a thyroid-specific transcription factor that binds to the thyroglobulin promoter and regulates thyroid-specific gene expression. It also influences genes involved in morphogenesis.
Mutations or deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, neonatal respiratory distress, and potentially thyroid cancer.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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