Thermo Fisher Scientific RET Recombinant Rabbit Monoclonal Antibody (009)
Human RET 단백질을 인식하는 Recombinant Rabbit Monoclonal Antibody로 ELISA에 최적화. HEK293 발현 시스템 사용, Protein A로 정제된 고순도 항체. PBS 저장 버퍼, 무보존제, -20°C 보관. 연구용 전용 제품으로 다양한 RET 관련 신호전달 연구에 활용 가능.
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Applications
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 009 |
| Immunogen | Recombinant Human RET protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912271 |
Product Specific Information
Specificity: Human RET
Target Information
The receptor tyrosine kinase RET is a member of the cadherin superfamily. RET plays a crucial role in neural crest development and can undergo oncogenic activation by cytogenetic rearrangement. RET transduces signals for cell growth and differentiation.
Mutations in the RET gene are associated with multiple endocrine neoplasia type IIA, type IIB, Hirschsprung disease, and medullary thyroid carcinoma.
Two transcript variants encoding different isoforms have been found for the RET gene. Additional transcript variants have been described for RET but their biological validity has not been confirmed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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