Thermo Fisher Scientific Pepsin A Recombinant Rabbit Monoclonal Antibody (021)
Recombinant rabbit monoclonal antibody against Pepsin A (clone 021). Specific to human PGA4, suitable for IHC (paraffin). Produced in HEK293 cells, purified via Protein A, liquid form at 1 mg/mL. For research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution
- 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 021 |
| Immunogen | Recombinant Human PGA4 Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912269 |
Product Specific Information
- Specificity: Human PGA4
Target Information
Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, produced by the gastric mucosa, is required to convert the inactive enzyme and maintain the optimal acidity (pH 1–3) for pepsin function.
Pepsin effectively cleaves peptide bonds involving aromatic amino acids and shows broad specificity, with phenylalanine and leucine bonds being most preferred.
Pepsin A belongs to the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. It is inhibited by ovUS-1, a uterine serpin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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