Thermo Fisher Scientific IL23R Monoclonal Antibody (15N6C6)
IL23R 단백질을 인식하는 Mouse monoclonal antibody (clone 15N6C6). Western blot 및 IHC(Paraffin) 검증 완료. Human 및 비인간 영장류 반응성. Protein G 정제, PBS buffer에 0.05% sodium azide 포함. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 15N6C6 |
| Immunogen | Synthetic peptide corresponding to amino acids 288–315 of Human IL-23 receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2717277 |
Target Information
IL-23R is a 629 amino acid subunit of the receptor for cytokine IL23A/IL23, which pairs with IL12RB1 (IL12R beta 1) and participates in IL23A signaling. It constitutively associates with Janus kinase 2 (JAK2) and binds transcription activator STAT3 in a ligand-dependent manner. Alternative splicing yields six isoforms of IL-23R. IL-23R is implicated in psoriasis pathogenesis and is a potential therapeutic target in inflammatory bowel disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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