Thermo Fisher Scientific CDKN3 Polyclonal Antibody
CDKN3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능하며, Human 및 Mouse 반응성을 가집니다. 고순도 Affinity Chromatography 정제 및 안정적 액상 형태로 제공됩니다.
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- PA5120764
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–69 of human CDKN3 (NP_005183.2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.217 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914336 |
Product Specific Information
Positive test controls include mouse liver.
The target is usually found in the following locations: cytoplasm, perinuclear region.
Immunogen sequence:
MKPPSSIQTS EFDSSDEEPI EDEQTPIHIS WLSLSRVNCS QFLGLCALPG CKFKDVRRNV QKDTEELKS
Target Information
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It acts as a cyclin-dependent kinase inhibitor, interacting with and dephosphorylating CDK2 kinase, thereby preventing its activation. This gene has been reported to be deleted, mutated, or overexpressed in several types of cancers. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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