Thermo Fisher Scientific SARS-CoV Spike Protein RBD Polyclonal Antibody
SARS-CoV-2 스파이크 단백질 RBD에 특이적인 토끼 폴리클로날 항체로, Western blot 및 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C에서 보관합니다. 연구용 전용 제품입니다.
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- PA5120762
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 350–450 of coronavirus Spike RBD (NP_8288511) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.15 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914334 |
Product Specific Information
- Positive test controls include: 293T cells.
- Immunogen sequence:
ADYSVLYNST FFSTFKCYGV SATKLNDLCF SNVYADSFVV KGDDVRQIAP GQTGVIADYN YKLPDDFMGC VLAWNTRNID ATSTGNYNYK YRYLRHGKLR P
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus responsible for illnesses ranging from mild cold symptoms to severe respiratory distress and death.
The coronavirus Spike (S) protein is crucial for viral attachment, fusion, and entry, making it a key target for antibody, inhibitor, and vaccine development.
The receptor-binding domain (RBD, S-RBD) of the Spike protein binds strongly to angiotensin-converting enzyme 2 (ACE2) receptors in humans and bats.
SARS-CoV-2 RBD shows significantly higher binding affinity to ACE2 compared to SARS-CoV RBD.
The S1 subunit contains the RBD that specifically interacts with ACE2 on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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