Thermo Fisher Scientific HCoV-NL63 Spike S2 Polyclonal Antibody
HCoV-NL63 Spike S2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 ELISA에 적합하며, 고순도 Affinity Chromatography로 정제됨. 안정적인 PBS/glycerol buffer에 보관하며 연구용으로 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1200–1300 of coronavirus Spike S2 (YP_0037671) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.49 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2914338 |
Product Specific Information
Positive test controls include: Human coronavirus (HCoV-NL63) Spike Protein (S1+S2 ECDHis Tag).
Immunogen sequence:
VNISRVELHT VIPDYVDVNK TLQEFAQNLP KYVKPNFDLT PFNLTYLNLS SELKQLEAKT ASLFQTTVEL QGLIDQINST YVDLKLLNRF ENYIKWPWWV W
Target Information
S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) form a trimer-of-hairpins structure, positioning the fusion peptide near the C-terminal region of the ectodomain. This structure drives apposition and subsequent fusion of viral and target cell membranes. [Uniprot]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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