Thermo Fisher Scientific Blood Group Antigen H Type 2 (CD173) Monoclonal Antibody (A46-B/B10)
Human 혈액형 항원 H Type 2(CD173)을 인식하는 mouse IgM 단일클론 항체로, IHC, ICC/IF, hemagglutination 및 competition assay에 사용 가능. Unconjugated 형태로 제공되며, 200 µg/mL 농도, PBS buffer에 0.05% BSA 및 sodium azide 포함. 4°C 보관, 동결 금지.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Blood Group Antigen H Type 2 (CD173) Monoclonal Antibody (A46-B/B10)
Thermo Fisher Scientific Blood Group Antigen H Type 2 (CD173) Monoclonal Antibody (A46-B/B10)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 2–4 µg/mL |
| Hemagglutination Assay (HA) | Assay-dependent |
| Competition Assay (CA) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A46-B/B10 |
| Immunogen | Human breast cancer MCF-7 cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The H antigen is a precursor to the ABO blood group antigens, present in people of all common blood types. The Bombay phenotype (hh) does not express antigen H on red blood cells and therefore lacks A or B antigens, similar to the O blood group. However, unlike the O group, the H antigen is absent, leading to production of isoantibodies to antigen H as well as A and B antigens.
If individuals with the Bombay phenotype receive blood from someone with O blood group, anti-H antibodies will bind to the H antigen on donor red blood cells and cause complement-mediated lysis. Thus, they can receive blood only from other hh donors but can donate as though they were type O.
The production of the H antigen, or its deficiency in the Bombay phenotype, is controlled at the H locus on chromosome 19. This locus encodes a fucosyltransferase responsible for producing the H antigen on RBCs. The H antigen is a carbohydrate sequence primarily linked to protein, with a minor fraction attached to a ceramide moiety.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(관련 항원 구조 이미지 및 제품 사진은 이 섹션에 배치됩니다.)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.