Thermo Fisher Scientific RTN4RL2 Recombinant Rabbit Monoclonal Antibody (P14)
RTN4RL2 단백질을 인식하는 재조합 토끼 단클론 항체로, WB, Flow, ELISA, IP 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. HEK293 세포에서 발현, Protein A로 정제된 액상 항체. 단기 4°C, 장기 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | P14 |
| Immunogen | (His)₆-tagged fragment of rat NgR2 (amino acids 279–420) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074380 |
Product Specific Information
- Specificity: The antibody binds to human NgR2 with a Kd of 2.3 nM and to rat NgR2 with a Kd of 0.48 nM (bivalent binding).
Target Information
Reticulon 4 receptor-like 2 (RTN4RL2), also known as NgR2 and NgRH1, is a 60 kDa glycosylphosphatidylinositol-anchored protein primarily expressed in the brain. It contains eight leucine-rich repeats flanked by cysteine-rich sequences at both termini. The membrane-anchored RTN4RL2 can be solubilized by phospholipase or an unidentified MTMMP to generate a 46 kDa soluble receptor. RTN4RL2 may play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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