Thermo Fisher Scientific CD63 Chimeric Recombinant Mouse Monoclonal Antibody (MOF11)
CD63 단백질을 인식하는 마우스 재조합 단클론 항체로, 인간 단핵구 및 활성화된 호중구에서 CD63을 검출. ICC/IF 및 유세포분석에 적합하며, 고순도 Protein A 정제 및 안정적 액상 형태로 제공. 연구용으로만 사용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 10 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MOF11 |
| Immunogen | Human monocytes |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074383 |
Product Specific Information
Specificity: This antibody binds to CD63 on monocytes and activated neutrophils.
Target Information
CD63 (LAMP-3, lysosome-associated membrane protein-3) is a glycoprotein of the tetraspanin family, found in late endosomes, lysosomes, and secretory vesicles. It is also present on the plasma membrane following cell activation and serves as a basophil activation marker. CD63 interacts with integrins, influencing phagocytosis and cell migration, and regulates H/K-ATPase trafficking and ROMK1 channels. Additionally, it functions as a T-cell costimulation molecule. CD63 expression can indicate carcinoma prognosis and is associated with melanoma and Hermansky-Pudlak Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(해당 항체의 면역원 관련 이미지: MA5-47939_CD63_P08962-1_House_mouse.svg / MA5-47939_CD63_P08962-1_House_mouse_PDP.jpeg)
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