Thermo Fisher Scientific PD-L1 (CD274) Recombinant Rat Monoclonal Antibody (YDC 127.1.1)
마우스 PD-L1에 특이적으로 결합하는 재조합 랫트 단클론 항체로, Flow Cytometry 등 연구용에 적합함. HEK293 세포에서 발현되며 Protein A로 정제된 고순도 항체. 장기 보관 시 -20°C에서 안정적으로 유지 가능.
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Thermo Fisher Scientific PD-L1 (CD274) Recombinant Rat Monoclonal Antibody (YDC 127.1.1)
Applications
- Flow Cytometry (Flow)
Tested Dilution
- Assay-dependent
Publications
- [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | YDC 127.1.1 |
| Immunogen | Murine PDL1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3074377 |
Product Specific Information
- Specificity: This antibody binds to murine PD-L1.
Target Information
Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon ligation, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 is abundantly expressed in murine and human cancers and can be up-regulated by IFN-gamma stimulation. Therefore, PD-L1 plays an important role in tumor immune evasion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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