Thermo Fisher Scientific TBK1 Polyclonal Antibody
TBK1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF, ELISA에 적합합니다. Human 및 Mouse에 반응하며, 친화 크로마토그래피로 정제되었습니다. -20°C에서 보관하며 반복 동결-해동은 피해야 합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | 1:100 |
| Immunocytochemistry (ICC/IF) | 15 µg/mL |
| ELISA | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Anti-TBK1 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal portion of human TBK1 conjugated to Keyhole Limpet Hemocyanin (KLH). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.02M potassium phosphate, pH 7.2, with 0.15M NaCl |
| Contains | 0.01% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing.
Centrifuge product if not completely clear after standing at room temperature.
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use.
This affinity purified antibody is directed against human TBK1. A BLAST analysis suggests cross-reactivity with mouse TBK1 based on 100% sequence homology.
Target Information
TBK1 serine/threonine kinase is a member of the IKK family involved in NF-kappa B activation and IRF3 signaling. It is an essential mediator of gene expression during immune and inflammatory responses.
Phosphorylation of I-KB by the IKK complex leads to NF-KB activation.
TBK1 (also known as TANK-binding kinase 1, NAK, or T2K) activates IKK beta through direct phosphorylation and mediates IKK and NF-kB activation in response to growth factors.
It also plays a critical role in protecting embryonic liver from apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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