Thermo Fisher Scientific H3K36me2 Polyclonal Antibody
H3K36me2 다이메틸화 히스톤 H3를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF에 적합하며 Human, Mouse, Rat 시료에서 반응. 고순도 친화 크로마토그래피 정제, PBS/glycerol buffer에 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human HIST3H3 (Accession Q16695), corresponding to amino acid residues T23–Y42 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899320 |
Product Specific Information
This antibody detects endogenous levels of Di-Methyl-Histone H3 only when methylated at Lys36.
Target Information
Histone H3 is a DNA-binding protein found in the chromatin of all eukaryotic cells. Together with four core histone proteins, it forms the nucleosome structure that packages DNA. Histones play crucial roles in transcription regulation, DNA repair, replication, and chromosomal stability. The N-terminal tail of histone H3 can undergo various post-translational modifications, such as methylation, acetylation, and phosphorylation, influencing chromatin structure and gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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