Thermo Fisher Scientific Cytokeratin 17 Monoclonal Antibody (A2B11)
Cytokeratin 17 단백질을 인식하는 Mouse monoclonal antibody(A2B11)로, Western blot, IHC, Flow cytometry에 적합. Human 시료 반응성. Protein G 정제, 1 mg/mL 농도. PBS/glycerol buffer에 보관, -20°C에서 저장 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A2B11 |
| Immunogen | Synthetic peptide within Human Cytokeratin 17 (aa 383–432) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848854 |
Product Specific Information
- Positive Control: SiHa cell lysates, human skin tissue.
Target Information
Cytokeratins are a subfamily of intermediate filament proteins characterized by biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between approximately 40 kDa and 68 kDa, with isoelectric points between 4.9 and 7.8.
Individual human cytokeratins are numbered 1 to 20. Expression patterns vary by epithelial type and differentiation stage, making them useful markers in distinguishing epithelial malignancies. Cytokeratin antibodies assist in tumor differential diagnosis via immunohistochemistry and are valuable in cytopathology and flow cytometric assays.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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