Thermo Fisher Scientific Thymidine Phosphorylase Monoclonal Antibody (A1A10)
인간 Thymidine Phosphorylase를 인식하는 Mouse monoclonal antibody (Clone A1A10). Western blot, IHC, Flow cytometry에 적합. Protein G로 정제된 액상 형태, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A1A10 |
| Immunogen | Recombinant protein within Human Thymidine Phosphorylase (aa 19–239) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848852 |
Product Specific Information
Positive Control: A549 cell, human liver carcinoma tissue, human spleen tissue, SiHa cell.
Target Information
Thymidine Phosphorylase (also known as PD-ECGF or gliostatin) is a platelet-derived endothelial growth factor.
It catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate in the presence of inorganic orthophosphate.
This enzyme is chemotactic and mitogenic for endothelial cells and acts as a non-heparin-binding angiogenic factor present in platelets.
It also plays a role in the transformation of fluoropyrimidines, cytotoxic agents used in cancer treatment, into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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