Thermo Fisher Scientific Thymidine Phosphorylase Monoclonal Antibody (A1A8)
Thymidine Phosphorylase 단백질을 인식하는 Mouse monoclonal antibody (clone A1A8). Western blot, IHC, Flow cytometry에 사용 가능. Human 시료 반응성. Protein G 정제, 2 mg/mL 농도, PBS/glycerol buffer 보존.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A1A8 |
| Immunogen | Recombinant protein within Human Thymidine Phosphorylase aa 19–239 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2848853 |
Product Specific Information
Positive Control: A549 cell, human liver carcinoma tissue, human appendix tissue, human spleen tissue, SiHa cell.
Target Information
Thymidine Phosphorylase (also known as PD-ECGF or gliostatin) is a platelet-derived endothelial growth factor. In the presence of inorganic orthophosphate, it catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It acts as a chemotactic and mitogenic factor for endothelial cells and functions as a non-heparin binding angiogenic factor present in platelets. It also plays a role in converting fluoropyrimidines, cytotoxic agents used in cancer therapy, into active cytotoxic metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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