Thermo Fisher Scientific IL17RA Recombinant Rabbit Monoclonal Antibody (012)
인간 IL17RA 단백질을 인식하는 재조합 토끼 단클론 항체입니다. ELISA에 적합하며 높은 특이성과 민감도를 제공합니다. 보존제가 포함되지 않아 오염 방지를 위해 sodium azide 첨가를 권장합니다. 단백질 A로 정제된 액상 형태로 제공됩니다.
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Applications
- ELISA (ELISA): 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 012 |
| Immunogen | Recombinant Human IL17RA protein (Met1–Trp320) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS |
| Contains | No preservative |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2786257 |
Product Specific Information
This product is preservative-free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
This antibody specifically recognizes Human IL17RA/CD217.
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes and induces maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17RA is a type I membrane glycoprotein that binds with low affinity to IL-17A and IL-17F. IL-17A and its receptor are implicated in inflammatory and autoimmune diseases such as rheumatoid arthritis. Defects in IL-17RA cause familial candidiasis type 5 (CANDF5), a rare disorder characterized by altered immune responses and impaired fungal clearance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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